Intelligent design in Science which featues dynen and kinesin

A dynein carrying cargo along a microtubule. Image courtesy of Wikipedia (Creative Commons Attribution 3.0 Unported license).

Joel Kontinen 

Hardly a week goes by without a paper on molecular machines being published in a major science journal. Recently, Science published a study on dynein and kinesin walk their way in our genome.

Fine-tuning is very much evident in its walk: dynein, which transports cargo by walking along a microtubule.

 This is what science says about the walkers: :  .

Controlling the long-range movement of molecules is challenging. cells use molecular motors such as dynein and kinesin and cytoskeletal features such as microtubules to achieve active transport over long distances relative to cargo sizes. taking inspiration from these natural systems, ibusuki et al. outfitted the motor protein dynein with a dna-binding module that enables it to grab onto and move along an engineered dna track  this system is attractive because the dna track can adopt precisely designed structures, and the dna-binding module creates specificity for different sequences. using these features, the authors created sorters that could separate cargos between two tracks and integrators that could bring together two streams of cargos. the average speed of the engineered motors is about 220 nanometers per second, comparable to some molecular motors in the cell. 

A kinesin motor does practically the same thing, but in the opposite or plus-end direction. Both the dynein and kinesin suggest that our cells work in anything but a haphazard way.

In other words, fine-tuning and amazing design are evident from start to finish.

 source;

march