Tuesday, 19 May 2026

Natural sunscreen found in fish eggs can be made by E. coli factories

 

Image courtesy of WILDLIFE GmbH / Alamy

Joel Kontinen

Intelligent design has provided  zebrafish eggs to produce a chemical that keeps the suns rays  from harming people. The chemical is known as gadusol.

A team led by Ping Zhang at Jiangnan University, China, inserted genes from zebrafish into the bacterium Escherichia coli to give it the enzymes needed to synthesise gadusol. Then, by using small RNA molecules to dial up gadusol production in the bacteria and tweaking their growing conditions, they increased the yield by nearly 93 times, from 45.2 milligrams per litre of liquid growth medium to 4.2 grams per litre.

In experiments, gadusol displayed antioxidant properties comparable to vitamin C, suggesting it may help neutralise free radicals that cause damage in cells.

Gadusol is transparent, unlike melanin, and yet is perfectly tuned to block out harmful UV rays from the sun, which makes it ideal for organisms hiding from prey. “I think we haven’t necessarily given it the praise that it deserves,” says James Gagnon at the University of Utah, who was part of a team that discovered gadusol’s role as a sunscreen in fish embryos. “This is a great molecule.”

Gadusol is found in the eggs of zebrafish, salmon and sturgeon, as well as coral, where it protects organisms from ultraviolet damage. But it’s only found in small quantities so extracting it from organisms for use as a sunscreen is impractical

Gagnon says further testing is needed, but the compound is likely to be safe for humans and the environment because so many animals already use it. Thanks to its transparency, it might also avoid the milky residue that some current sunscreens leave on the skin.

“Everyone wants to hint that this is going to be a great sunscreen for humans,” says Gagnon.

Source:

 Matthew Sparkes 2026 Natural sunscreen found in fish eggs can be made by E. coli factories | New Scientist 13 May