Friday, 31 October 2025

Denisovans may have interbred with mysterious group of ancient humans

 


Illustration of a teenage girl who is the offspring of a Neanderthal mother and Denisovan father. Image courtesy of John Bavaro Fine Art/Science Photo Library

Joel Kontinen

For only the second time, researchers have obtained the full genome of a Denisovan, a group of ancient humans who lived in Asia. The DNA was extracted from a single 200,000-year-old tooth found in a Siberian cave.

Denisovans were the first ancient humans to be described using just DNA. A sliver of finger bone from Denisova cave in Siberia held DNA unlike that of either modern humans or the Neanderthals from western Eurasia. The genome revealed that Denisovans interbred with modern humans: people in South-East Asia, including the Philippines and Papua New Guinea, carry Denisovan DNA.

Based on the number of mutations in the genome and comparisons to other ancient humans, the team estimated that the individual lived about 205,000 years ago. In line with this, the sediments in which the tooth was found were dated to 170,000-200,000 years ago. In contrast, the other high-quality genome is from a Denisovan who lived 55,000-75,000 years ago, meaning that the new genome reveals a much earlier stage of Denisovan history.

Based on comparisons with other remains from Denisova cave, the team says there seem to have been at least three discrete Denisovan populations. The oldest group included the male whose tooth was analysed. A second group replaced this older population at Denisova cave, thousands of years later.

The third group, not represented at the cave, interbred with modern humans, based on DNA testing. In other words, all the Denisovan DNA in modern humans comes from a population of Denisovans that we know little or nothing about.

The new genome reveals that Denisovans repeatedly interbred with Neanderthals, who sometimes lived in or near Denisova cave.

The Denisovans also seem to have interbred with an unidentified group of humans. They might also  have interbred with Homo erectus.

According to Genesis, we all are members of the human  race,  the  descendants of Adam  and Eve.

Source:

Michael Marshall 2025 Denisovans may have interbred with mysterious group of ancient humans | New Scientist 31 October